China-Coronavirus/Portable Test Kit

Chinese experts working to develop portable test kit, new treatment options for COVID-19

  • English

Shotlist


Beijing, China - June 24, 2020 (CGTN - No access Chinese mainland)
1. Various of Bai Jingwei, Associate Professor, School of Pharmaceutical Science, Tsinghua University, introducing portable COVID-19 test kit
2. Graphic showing how portable COVID-19 test kit works
3. SOUNDBITE (English) Bai Jingwei, Associate Professor, School of Pharmaceutical Science, Tsinghua University (partially overlaid with shots 4-5):
"Inside this box we have a chemistry [technique] called isothermal amplification. We invent a nested isothermal amplification application to achieve a large quantity of very, very high sensitivity of application and detection."
++SHOTS OVERLAYING SOUNDBITE++
4. Portable COVID-19 test kit
5. Ding Sheng, Dean, School of Pharmaceutical Sciences, Tsinghua University, listening
++SHOTS OVERLAYING SOUNDBITE++
6. Various of photos of Bai, other colleagues, presenting portable COVID-19 test kit
7. SOUNDBITE (English) Ding Sheng, Dean, School of Pharmaceutical Sciences, Tsinghua University (starting with shot 6, partially overlaid with shot 8):
"I would say the biggest advantage of this small device is really [that] you don't really need any instrument actually to do nucleic acid detection. Actually, for any other diagnostic for COVID-19 products [or] for any nucleic detection all require a specific instrument, that's not actually convenient."
++SHOT OVERLAYING SOUNDBITE++
8. Reporter
++SHOT OVERLAYING SOUNDBITE++
9. Reporter, Ding, talking outside lab
10. SOUNDBITE (English) Tan Xu, Associate Professor, School of Pharmaceutical Science, Tsinghua University (partially overlaid with shots 11-12):
"We hope to identify some broad spectrum anti-virus [treatment] that will work not only for COVID-19 but also for other viruses. Maybe for a virus that will cause an epidemic in the future even. So we study how virus enter into human cells and how it replicates in human cells. Actually that process is very complex, it needs help of a lot of your own genes or your own protein to do work for them. So many different viruses actually utilize or may hijack similar human proteins for their own use. So if you can block those common used so-called 'host' factors, you might have some idea how to make new drugs that not only block one specific virus, but many different other viruses. But that's what we do, we look for those genes, human genes that are used by what the viruses to replicate themselves."
++SHOTS OVERLAYING SOUNDBITE++
11. Various of researchers working in lab
12. Reporter, Ding
++SHOTS OVERLAYING SOUNDBITE++
13. Various of labs
14. Various of researchers working in lab

Storyline


Chinese experts have been working round the clock to develop new solutions to better detect and offer treatment for COVID-19, with a potentially revolutionary portable easy-use testing kit under development which would allow individuals to see results in a matter of minutes.

As global infections surpass the 10 million mark, the development of the portable nucleic acid test kit and research into new antibiotic drugs for treating COVID-19 are among the latest efforts Chinese experts are making to the global fight to curb the virus.

The portable nucleic acid test kit developed by researchers from Tsinghua University's school of Pharmaceutical Science is expected to reduce both the cost and time required compared to present testing methods.

The design also lowers the risk of cross contamination, with the kit designated for one-time individual use, and easy enough to be taken at home.

"Inside this box we have a chemistry [technique] called isothermal amplification. We invent a nested isothermal amplification application to achieve a large quantity of very, very high sensitivity of application and detection," said Bai Jingwei, an associate professor involved in the development of the test kit.

Once completed, it will only take about 10 minutes for the result to be read out on the small device, while the usual polymerase chain reaction (PCR) test used to detect COVID-19 takes many hours or even days to obtain results.

Ding Sheng, the dean of the School of Pharmaceutical Science at Tsinghua University, said that compared with a traditional PCR test, the new kit is easier to operate by an individual without specific relevant medical knowledge.

"I would say the biggest advantage of this small device is really [that] you don't really need any instrument actually to do nucleic acid detection. Actually, for any other diagnostic for COVID-19 products [or] for any nucleic detection all require a specific instrument, that's not actually convenient," he said.

In addition to the portable test kit, researchers from the university are also working to find possible new antibiotic drugs which can help treat COVID-19.

Tan Xu, another associate professor at Tsinghua University, has been doing a study on viral host interactions as he looks to find the right target for developing anti-viral small molecule drugs.

"We hope to identify some broad spectrum anti-virus [treatment] that will work not only for COVID-19 but also for other viruses. Maybe for a virus that will cause an epidemic in the future even. So we study how virus enter into human cells and how it replicates in human cells. Actually that process is very complex, it needs help of a lot of your own genes or your own protein to do work for them. So many different viruses actually utilize or may hijack similar human proteins for their own use. So if you can block those common used so-called 'host' factors, you might have some idea how to make new drugs that not only block one specific virus, but many different other viruses. But that's what we do, we look for those genes, human genes that are used by what the viruses to replicate themselves," said Tan.

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  • ID : 8148362
  • Published : 2020-06-30 16:23
  • Last Modified : 2020-06-30 17:53:53
  • Location : Beijing,China
  • Category : health,science and technology
  • Duration : 2'23
  • Audio Language : English/Nats
  • Source : China Global Television Network (CGTN)
  • Restrictions : No access Chinese mainland
  • Version : 3

China-Coronavirus/Portable Test Kit

Chinese experts working to develop portable test kit, new treatment options for COVID-19

Dateline : June 24, 2020

Location : Beijing,China

Duration : 2'23

  • English


Beijing, China - June 24, 2020 (CGTN - No access Chinese mainland)
1. Various of Bai Jingwei, Associate Professor, School of Pharmaceutical Science, Tsinghua University, introducing portable COVID-19 test kit
2. Graphic showing how portable COVID-19 test kit works
3. SOUNDBITE (English) Bai Jingwei, Associate Professor, School of Pharmaceutical Science, Tsinghua University (partially overlaid with shots 4-5):
"Inside this box we have a chemistry [technique] called isothermal amplification. We invent a nested isothermal amplification application to achieve a large quantity of very, very high sensitivity of application and detection."
++SHOTS OVERLAYING SOUNDBITE++
4. Portable COVID-19 test kit
5. Ding Sheng, Dean, School of Pharmaceutical Sciences, Tsinghua University, listening
++SHOTS OVERLAYING SOUNDBITE++
6. Various of photos of Bai, other colleagues, presenting portable COVID-19 test kit
7. SOUNDBITE (English) Ding Sheng, Dean, School of Pharmaceutical Sciences, Tsinghua University (starting with shot 6, partially overlaid with shot 8):
"I would say the biggest advantage of this small device is really [that] you don't really need any instrument actually to do nucleic acid detection. Actually, for any other diagnostic for COVID-19 products [or] for any nucleic detection all require a specific instrument, that's not actually convenient."
++SHOT OVERLAYING SOUNDBITE++
8. Reporter
++SHOT OVERLAYING SOUNDBITE++
9. Reporter, Ding, talking outside lab
10. SOUNDBITE (English) Tan Xu, Associate Professor, School of Pharmaceutical Science, Tsinghua University (partially overlaid with shots 11-12):
"We hope to identify some broad spectrum anti-virus [treatment] that will work not only for COVID-19 but also for other viruses. Maybe for a virus that will cause an epidemic in the future even. So we study how virus enter into human cells and how it replicates in human cells. Actually that process is very complex, it needs help of a lot of your own genes or your own protein to do work for them. So many different viruses actually utilize or may hijack similar human proteins for their own use. So if you can block those common used so-called 'host' factors, you might have some idea how to make new drugs that not only block one specific virus, but many different other viruses. But that's what we do, we look for those genes, human genes that are used by what the viruses to replicate themselves."
++SHOTS OVERLAYING SOUNDBITE++
11. Various of researchers working in lab
12. Reporter, Ding
++SHOTS OVERLAYING SOUNDBITE++
13. Various of labs
14. Various of researchers working in lab


Chinese experts have been working round the clock to develop new solutions to better detect and offer treatment for COVID-19, with a potentially revolutionary portable easy-use testing kit under development which would allow individuals to see results in a matter of minutes.

As global infections surpass the 10 million mark, the development of the portable nucleic acid test kit and research into new antibiotic drugs for treating COVID-19 are among the latest efforts Chinese experts are making to the global fight to curb the virus.

The portable nucleic acid test kit developed by researchers from Tsinghua University's school of Pharmaceutical Science is expected to reduce both the cost and time required compared to present testing methods.

The design also lowers the risk of cross contamination, with the kit designated for one-time individual use, and easy enough to be taken at home.

"Inside this box we have a chemistry [technique] called isothermal amplification. We invent a nested isothermal amplification application to achieve a large quantity of very, very high sensitivity of application and detection," said Bai Jingwei, an associate professor involved in the development of the test kit.

Once completed, it will only take about 10 minutes for the result to be read out on the small device, while the usual polymerase chain reaction (PCR) test used to detect COVID-19 takes many hours or even days to obtain results.

Ding Sheng, the dean of the School of Pharmaceutical Science at Tsinghua University, said that compared with a traditional PCR test, the new kit is easier to operate by an individual without specific relevant medical knowledge.

"I would say the biggest advantage of this small device is really [that] you don't really need any instrument actually to do nucleic acid detection. Actually, for any other diagnostic for COVID-19 products [or] for any nucleic detection all require a specific instrument, that's not actually convenient," he said.

In addition to the portable test kit, researchers from the university are also working to find possible new antibiotic drugs which can help treat COVID-19.

Tan Xu, another associate professor at Tsinghua University, has been doing a study on viral host interactions as he looks to find the right target for developing anti-viral small molecule drugs.

"We hope to identify some broad spectrum anti-virus [treatment] that will work not only for COVID-19 but also for other viruses. Maybe for a virus that will cause an epidemic in the future even. So we study how virus enter into human cells and how it replicates in human cells. Actually that process is very complex, it needs help of a lot of your own genes or your own protein to do work for them. So many different viruses actually utilize or may hijack similar human proteins for their own use. So if you can block those common used so-called 'host' factors, you might have some idea how to make new drugs that not only block one specific virus, but many different other viruses. But that's what we do, we look for those genes, human genes that are used by what the viruses to replicate themselves," said Tan.

ID : 8148362

Published : 2020-06-30 16:23

Last Modified : 2020-06-30 17:53:53

Source : China Global Television Network (CGTN)

Restrictions : No access Chinese mainland

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